Splenic marginal zone lymphoma in a HIV-1 infected patient: evidence favouring a pathogenetic role of HIV-1 itself in the lymphomagenesis

被引：3

作者：

Cagliuso, M. ^{[1
]}

Conti, V. ^{[1
]}

Trasarti, S. ^{[2
]}

Lombardi, L. ^{[2
]}

Riminucci, M. ^{[3
]}

Perez, M. ^{[4
]}

Turriziani, O. ^{[3
]}

Falasca, F. ^{[3
]}

Nanni, M. ^{[2
]}

Tafuri, A. ^{[2
]}

Mezzaroma, I. ^{[1
]}

机构：

[1] Univ Roma La Sapienza, Dept Clin Med, I-00185 Rome, Italy

[2] Univ Roma La Sapienza, Dept Cellular Biotechnol & Hematol, I-00185 Rome, Italy

[3] Univ Roma La Sapienza, Dept Mol Med, I-00185 Rome, Italy

[4] IRCCS, Lab Histopathol, Ist Dermopat Immacolata, Rome, Italy

来源：

INFECTION | 2013年 / 41卷 / 01期

关键词：

HIV-1; SMZLs; Splenomegaly; B-CELL LYMPHOMA; INFECTION; VIRUS; AIDS; DISEASE;

D O I：

10.1007/s15010-012-0344-4

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

A rare case of splenic marginal zone lymphoma (SMZL) in a human immunodeficiency virus (HIV)-1 infected patient is described. As an association between SMZL and viral infections has been reported, the presence of the hepatitis C virus and HIV-1 genomes was evaluated. Only HIV-1 DNA levels were detected in enriched splenic B lymphocytes, suggesting a HIV-1 involvement in lymphomagenesis.

引用

页码：255 / 258

页数：4

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