Modified wound dressing with phyto-nanostructured coating to prevent staphylococcal and pseudomonal biofilm development

被引:68
作者
Anghel, Ion [1 ,5 ]
Holban, Alina Maria [2 ]
Grumezescu, Alexandru Mihai [3 ]
Andronescu, Ecaterina [3 ]
Ficai, Anton [3 ]
Anghel, Alina Georgiana [1 ]
Maganu, Maria [4 ]
Lazar, Veronica [2 ]
Chifiriuc, Mariana Carmen [2 ]
机构
[1] Carol Davila Univ Med & Pharm, Coltea Hosp, ENT Otolaryngol Dept, Bucharest 030171, Romania
[2] Univ Bucharest, Fac Biol, Dept Microbiol, Bucharest 060101, Romania
[3] Univ Politehn Bucuresti, Fac Appl Chem & Mat Sci, Dept Sci & Engn Oxid Mat & Nanomat, Bucharest 011061, Romania
[4] Romanian Acad, Ctr Organ Chem Costin D Nenitescu, Bucharest 050461, Romania
[5] Doctor Anghel Med Ctr, Bucharest 30932, Romania
来源
NANOSCALE RESEARCH LETTERS | 2012年 / 7卷
关键词
Magnetite nanoparticles; Eugenol; Limonene; Wound dressing; OFFICINALIS ESSENTIAL OIL; MAGNETIC CHITOSAN; AERUGINOSA; DEXTRAN; NANOSYSTEM; EVOLUTION; ADHERENCE; VIRULENCE; INHIBIT;
D O I
10.1186/1556-276X-7-690
中图分类号
TB3 [工程材料学];
学科分类号
0805 ; 080502 ;
摘要
This paper reports a newly fabricated nanophyto-modified wound dressing with microbicidal and anti-adherence properties. Nanofluid-based magnetite doped with eugenol or limonene was used to fabricate modified wound dressings. Nanostructure coated materials were characterized by TEM, XRD, and FT-IR. For the quantitative measurement of biofilm-embedded microbial cells, a culture-based method for viable cell count was used. The optimized textile dressing samples proved to be more resistant to staphylococcal and pseudomonal colonization and biofilm formation compared to the uncoated controls. The functionalized surfaces for wound dressing seems to be a very useful tool for the prevention of wound microbial contamination on viable tissues.
引用
收藏
页码:1 / 8
页数:8
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