Autophagy downregulates thrombin-induced VSMCs proliferation through lysosomal pathway

被引：11

作者：

Dong, Nan ^{[1
]}

Zhu, Qian ^{[1
]}

Zhang, Peipei ^{[1
]}

Zhu, Chunfang ^{[1
]}

Wang, MinChen ^{[1
]}

Li, Wenjie ^{[1
]}

Liu, Juan ^{[1
]}

Liu, YanMei ^{[1
]}

Ma, Bin ^{[1
]}

Wu, Kaiyun ^{[1
]}

机构：

[1] Soochow Univ, Coll Med, Dept Anat, Suzhou 215123, Jiangsu, Peoples R China

来源：

INTERNATIONAL JOURNAL OF CARDIOLOGY | 2012年 / 159卷 / 02期

关键词：

Atherosclerosis; VSMCs; Proliferation; Autophagy; Thrombin; MTOR;

D O I：

10.1016/j.ijcard.2012.05.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：156 / 158

页数：3

共 9 条

[1] PROTEIN-SYNTHESIS AND DEGRADATION IN GROWTH-REGULATION IN RAT EMBRYO FIBROBLASTS - ROLE OF FAST-TURNOVER AND SLOW-TURNOVER PROTEIN [J].

AMENTA, JS ;

SARGUS, MJ ;

BROCHER, SC .

JOURNAL OF CELLULAR PHYSIOLOGY, 1980, 105 (01) :51-61

[2] Role and regulation of autophagy in cancer [J].

Chen, Ning ;

Karantza-Wadsworth, Vassiliki .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2009, 1793 (09) :1516-1523

[3] Oxidative stress and autophagy [J].

Kiffin, R ;

Bandyopadhyay, U ;

Cuervo, AM .

ANTIOXIDANTS & REDOX SIGNALING, 2006, 8 (1-2) :152-162

[4] Autophagy in the pathogenesis of disease [J].

Levine, Beth ;

Kroemer, Guido .

CELL, 2008, 132 (01) :27-42

[5] Autophagy in Atherosclerosis A Cell Survival and Death Phenomenon With Therapeutic Potential [J].

Martinet, Wim ;

De Meyer, Guido R. Y. .

CIRCULATION RESEARCH, 2009, 104 (03) :304-317

[6]

Mita MM, 2003, CANCER BIOL THER, V2, pS169

[7] INSOLUBLE LIPIDS IN HUMAN ATHEROSCLEROTIC PLAQUES [J].

MITCHINSON, MJ .

ATHEROSCLEROSIS, 1982, 45 (01) :11-15

[8] ARF, autophagy and tumor suppression [J].

Pimkina, Julia ;

Murphy, Maureen E. .

AUTOPHAGY, 2009, 5 (03) :397-399

[9] Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein [J].

Sarkar, Sovan ;

Davies, Janet E. ;

Huang, Zebo ;

Tunnacliffe, Alan ;

Rubinsztein, David C. .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (08) :5641-5652

← 1 →