Antibody-dependent cancer cell phagocytosis in macrophages induces immune escape by upregulating PD-L1 and IDO

被引：0
|
作者：
Su, Shicheng [1 ]
Su, An [1 ]
机构：
[1] Guangdong Prov Key Lab Malignant Tumor Epigenet &, Guangzhou, Peoples R China
来源：
CANCER IMMUNOLOGY RESEARCH | 2019年 / 7卷 / 02期
关键词：
D O I：
10.1158/2326-6074.CRICIMTEATIAACR18-A155
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
A155
引用
收藏
页数：2
相关论文
共 50 条
  • [41] Progranulin induces immune escape in breast cancer via up-regulating PD-L1 expression on tumor-associated macrophages (TAMs) and promoting CD8+ T cell exclusion
    Wenli Fang
    Ting Zhou
    He Shi
    Mengli Yao
    Dian Zhang
    Husun Qian
    Qian Zeng
    Yange Wang
    Fangfang Jin
    Chengsen Chai
    Tingmei Chen
    Journal of Experimental & Clinical Cancer Research, 40
  • [42] Anti-tumor effects of NK cells and anti-PD-L1 antibody with antibody-dependent cellular cytotoxicity in PD-L1-positive cancer cell lines
    Park, Ji-Eun
    Kim, Seong-Eun
    Keam, Bhumsuk
    Park, Ha-Ram
    Kim, Soyeon
    Kim, Miso
    Kim, Tae Min
    Doh, Junsang
    Kim, Dong-Wan
    Heo, Dae Seog
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2020, 8 (02)
  • [43] Hepatoma cell-intrinsic TLR9 activation induces immune escape through PD-L1 upregulation in hepatocellular carcinoma
    Zhou, Binghai
    Yan, Jiuliang
    Guo, Lei
    Zhang, Bo
    Liu, Shuang
    Yu, Mincheng
    Chen, Zheng
    Zhang, Kewei
    Zhang, Wentao
    Li, Xiaoqiang
    Xu, Yongfeng
    Xiao, Yongsheng
    Zhou, Jian
    Fan, Jia
    Hung, Mien-Chie
    Li, Hui
    Ye, Qinghai
    THERANOSTICS, 2020, 10 (14): : 6530 - 6543
  • [44] Novel Small-Molecule PD-L1 Inhibitor Induces PD-L1 Internalization and Optimizes the Immune Microenvironment
    Sun, Chengliang
    Yin, Mingxiao
    Cheng, Yao
    Kuang, Zean
    Liu, Xiaojia
    Wang, Gefei
    Wang, Xiao
    Yuan, Kai
    Min, Wenjian
    Dong, Jingwen
    Hou, Yi
    Hu, Lingrong
    Zhang, Guoyu
    Pei, Wenli
    Wang, Liping
    Sun, Yanze
    Yu, Xinmiao
    Xiao, Yibei
    Deng, Hongbin
    Yang, Peng
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (03) : 2064 - 2083
  • [45] Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancer
    Shao, Yiqun
    Zhu, Wenjing
    Da, Jun
    Xu, Mingxi
    Wang, Yiwei
    Zhou, Juan
    Wang, Zhong
    ONCOTARGETS AND THERAPY, 2017, 10 : 2675 - 2683
  • [46] PD-L1 antibody drug conjugate for cancer immune-chemo combination therapy
    Sau, Samaresh
    Petrovici, Alex
    Alsaab, Hashem
    Iyer, Arun K.
    CANCER RESEARCH, 2018, 78 (13)
  • [47] HIV-1 Evades Antibody-dependent Cell-mediated Phagocytosis in Monocytes
    Gach, Johannes S.
    Gorlani, Andrea
    Forthal, Donald N.
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2016, 32 : 137 - 137
  • [48] Targeting CTLA-4, PD-L1 and IDO to modulate immune responses in vitiligo
    Speeckaert, Reinhart
    van Geel, Nanja
    EXPERIMENTAL DERMATOLOGY, 2017, 26 (07) : 630 - 634
  • [49] Landscape of Immune Checkpoint Inhibition in Carcinosarcoma (MMMT): Analysis of IDO-1, PD-L1 and PD-1
    Hacking, Sean
    Chavarria, Hector
    Jin, Cao
    Perry, Alexander
    Nasim, Mansoor
    PATHOLOGY RESEARCH AND PRACTICE, 2020, 216 (04)
  • [50] The PD-L1 and OX40 bispecific antibody IBI327 induces immune activation and improves cancer immunotherapy
    Chen, Bingliang
    Kuang, Zhihui
    Li, Yiming
    Zhou, Shuaixiang
    Wu, Zhihai
    Wu, Min
    Yu, Michael
    Liu, Junjian
    CANCER RESEARCH, 2020, 80 (16)
12345