Nanostructured hydrogels for three-dimensional cell culture through self-assembly of fluorenylmethoxycarbonyl-dipeptides

被引：905

作者：

Jayawarna, V

Ali, M

Jowitt, TA

Miller, AE

Saiani, A

Gough, JE

Ulijn, RV

机构：

[1] Univ Manchester, Sch Mat, Manchester M1 7HS, Lancs, England

[2] Univ Manchester, Fac Life Sci, Manchester M1 7HS, Lancs, England

[3] Univ Manchester, Sch Chem Engn & Analyt Sci, Manchester M1 7HS, Lancs, England

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 05期

关键词：

D O I：

10.1002/adma.200501522

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A number of short peptide amphiphiles consisting of dipeptides linked to fluorenylmethoxycarbonyl spontaneously form fibrous hydrogels under physiological conditions (see figure). The structural and physical properties of these gels are dictated by the amino acid sequence of the peptide building blocks, and the gels support the three-dimensional cell culture of chondrocytes.

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页码：611 / +

页数：5

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