Evaluation of nuclear reaction cross-sections and fragment yields in carbon beams using the SHIELD-HIT Monte Carlo code. Comparison with experiments

被引:12
作者
Hultqvist, Martha [1 ]
Lazzeroni, Marta [2 ]
Botvina, Alexander [3 ,4 ]
Gudowska, Irena [1 ]
Sobolevsky, Nikolai [4 ]
Brahme, Anders [2 ]
机构
[1] Stockholm Univ, Dept Phys, SE-17176 Stockholm, Sweden
[2] Karolinska Inst, Dept Oncol Pathol, SE-17176 Stockholm, Sweden
[3] Goethe Univ Frankfurt, Frankfurt Inst Adv Studies, D-60438 Frankfurt, Germany
[4] Russian Acad Sci, Inst Nucl Res, Moscow 117312, Russia
关键词
TISSUE-LIKE MEDIA; DOSE DISTRIBUTIONS; TOTAL CHARGE; FLUKA CODE; ION-BEAMS; BREAK-UP; GEANT4; TRANSPORT; MODEL; C-12;
D O I
10.1088/0031-9155/57/13/4369
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
In light ion therapy, the knowledge of the spectra of both primary and secondary particles in the target volume is needed in order to accurately describe the treatment. The transport of ions in matter is complex and comprises both atomic and nuclear processes involving primary and secondary ions produced in the cascade of events. One of the critical issues in the simulation of ion transport is the modeling of inelastic nuclear reaction processes, in which projectile nuclei interact with target nuclei and give rise to nuclear fragments. In the Monte Carlo code SHIELD-HIT, inelastic nuclear reactions are described by the Many Stage Dynamical Model (MSDM), which includes models for the different stages of the interaction process. In this work, the capability of SHIELD-HIT to simulate the nuclear fragmentation of carbon ions in tissue-like materials was studied. The value of the parameter., which determines the so-called freeze-out volume in the Fermi break-up stage of the nuclear interaction process, was adjusted in order to achieve better agreement with experimental data. In this paper, results are shown both with the default value k = 1 and the modified value k = 10 which resulted in the best overall agreement. Comparisons with published experimental data were made in terms of total and partial charge-changing cross-sections generated by the MSDM, as well as integral and differential fragment yields simulated by SHIELD-HIT in intermediate and thick water targets irradiated with a beam of 400 MeV u(-1) C-12 ions. Better agreement with the experimental data was in general obtained with the modified parameter value (k = 10), both on the level of partial charge-changing cross-sections and fragment yields.
引用
收藏
页码:4369 / 4385
页数:17
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