Pallidotomy after chronic deep brain stimulation

被引：17
作者：
Bulluss, Kristian J.
Pereira, Erlick A.
Joint, Carole
Aziz, Tipu Z.
机构：
[1] Univ Oxford, Nuffield Dept Surg, Oxford Funct Neurosurg & Expt Neurol Grp, Oxford, England
[2] John Radcliffe Hosp, Dept Neurol Surg, Oxford OX3 9DU, England
来源：
NEUROSURGICAL FOCUS | 2013年 / 35卷 / 05期
关键词：
subthalamic nucleus; globus pallidus internus; deep brain stimulation; pallidotomy; PARKINSONS-DISEASE; POSTEROVENTRAL PALLIDOTOMY; BILATERAL PALLIDOTOMY; MOVEMENT-DISORDERS; THERAPY; TRIAL;
D O I：
10.3171/2013.8.FOCUS13293
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Recent publications have demonstrated that deep brain stimulation for Parkinson's disease still exerts beneficial effects on tremor, rigidity, and bradykinesia for up to 10 years after implantation of the stimulator. However with the progression of Parkinson's disease, features such as cognitive decline or "freezing" become prominent, and the presence of an implanted and functioning deep brain stimulator can impose a profound burden of care on the clinical team and family. The authors describe their experience in treating 4 patients who underwent removal of the implanted device due to either progressive dementia requiring full-time nursing or due to infection, and who subsequently underwent a unilateral pallidotomy.
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页数：4
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