Study of arterial stiffness in patients with an acute coronary event and chronic obstructive pulmonary disease confirmed by spirometry

被引：3

作者：

Almagro, P. ^{[1
,2
]}

Acosta, E. ^{[2
]}

Navarro, A. ^{[3
]}

Murillo, M. F. ^{[2
]}

Valdivielso, S. ^{[4
]}

de la Sierra, A. ^{[2
]}

机构：

[1] Univ Barcelona, Hosp Univ Mutua Terrasa, Unidad Pacientes Cron Cornplejos, Dept Med Interna, Barcelona, Spain

[2] Univ Barcelona, Hosp Univ Mutua Terrasa, Dept Med Interna, Barcelona, Spain

[3] Univ Barcelona, Hosp Univ Mutua Terrasa, Serv Neumol, Barcelona, Spain

[4] Univ Barcelona, Hosp Univ Mutua Terrasa, Serv Cardiol, Barcelona, Spain

来源：

REVISTA CLINICA ESPANOLA | 2019年 / 219卷 / 05期

关键词：

Chronic obstructive pulmonary disease; Ischaemic heart disease; Arterial stiffness; Pulse wave velocity; Cardio-ankle vascular index; Percutaneous coronary intervention; CARDIOVASCULAR RISK; PROGNOSIS; MORTALITY; OUTCOMES; IMPACT; COPD;

D O I：

10.1016/j.rce.2018.08.007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and objectives: Chronic obstructive pulmonary disease (COPD) worsens the prognosis for patients with an acute coronary event (ACE) treated with percutaneous coronary intervention. Objective To assess the effect of COPD on arterial stiffness in patients with an ACE. Methods: The study included patients with an ACE treated with percutaneous coronary intervention. At 1 month, postbronchodilation spirometry was performed, and arterial stiffness and markers of myocardial damage (troponin T and ProBNP) were measured. Results: We included 68 patients, 33% of whom had COPD (59% undiagnosed). The patients with COPD presented higher arterial stiffness values after adjusting for age and blood pressure readings. The troponin T and ProBNP levels were higher in the patients with COPD. Conclusions: Arterial stiffness is greater in patients with an ACE if they have concomitant COPD. These findings can help explain the poorer prognosis of patients with both conditions. (C) 2018 Published by Elsevier Espana, S.L.U.

引用

页码：251 / 255

页数：5

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