Silver-Catalyzed Nitrogenation of Alkynes: A Direct Approach to Nitriles through CC Bond Cleavage

被引：157
作者：
Shen, Tao [1 ]
Wang, Teng [1 ]
Qin, Chong [1 ]
Jiao, Ning [1 ,2 ]
机构：
[1] Peking Univ, State Key Lab Nat & Biomimet Drugs, Sch Pharmaceut Sci, Beijing 100191, Peoples R China
[2] Chinese Acad Sci, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 26期
基金：
美国国家科学基金会;
关键词：
alkynes; azides; nitriles; rearrangement; silver; CARBON TRIPLE BOND; EFFICIENT TRANSFORMATION; MOLECULAR-OXYGEN; AZIDE; ARYL; METATHESIS; COPPER; CYANATION; OXIDATION; ALKENES;
D O I：
10.1002/anie.201300193
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Three in one blow! A novel direct transformation of alkynes into nitriles by a silver-catalyzed nitrogenation reaction through C≡C bond cleavage has been developed. This research provides both a new application for alkynes in organic synthesis, and valuable mechanistic insights into nitrogenation chemistry. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：6677 / 6680
页数：4
相关论文
共 115 条
[1]   Cu(I)-Catalyzed Huisgen Azide-Alkyne 1,3-Dipolar Cycloaddition Reaction in Nucleoside, Nucleotide, and Oligonucleotide Chemistry [J].
Amblard, Franck ;
Cho, Jong Hyun ;
Schinazi, Raymond F. .
CHEMICAL REVIEWS, 2009, 109 (09) :4207-4220
[2]  
[Anonymous], 2009, ANGEW CHEM INT ED, V48, P8247
[3]  
[Anonymous], 2013, ANGEW CHEM INT ED, V52, P1507
[4]  
[Anonymous], 2011, ANGEW CHEM INT ED, V50, P11487
[5]  
[Anonymous], 2011, ANGEW CHEM INT ED, V50, P5927
[6]  
[Anonymous], 2007, ANGEW CHEM INT ED, V46, P3922
[7]  
[Anonymous], 2010, ANGEW CHEM INT ED, V49, P2096
[8]  
[Anonymous], 2011, ANGEW CHEM
[9]  
[Anonymous], ANGEW CHEM
[10]  
[Anonymous], 2009, ANGEW CHEM INT ED, V48, P7094
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