Platelets, petechiae, and preservation of the vascular wall

被引:187
作者
Nachman, Ralph L. [1 ]
Rafii, Shahin [1 ]
机构
[1] Weill Cornell Med Coll, New York, NY 10065 USA
关键词
D O I
10.1056/NEJMra0800887
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This review concerns functional contacts between platelets and endothelial cells, with emphasis on the maintenance of vascular integrity by proangiogenic cytokines and growth factors released by platelets. These molecules bind to receptors on the surface of endothelial cells, thereby stabilizing the vascular-endothelium cadherin complex. Copyright © 2008 Massachusetts Medical Society. All rights reserved.
引用
收藏
页码:1261 / 1270
页数:10
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