Enantioselective synthesis of martinelline chiral core and its diastereomer using asymmetric tandem Michael-aldol reaction

被引：48

作者：

Yoshitomi, Yayoi ^{[1
]}

Arai, Hiromi ^{[1
]}

Makino, Kazuishi ^{[1
]}

Hamada, Yasumasa ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Pharmaceut Sci, Inage Ku, Chiba 2638522, Japan

来源：

TETRAHEDRON | 2008年 / 64卷 / 51期

关键词：

Martinelline; Martinellic acid; Tandem Michael-aldol reaction; Organocatalyst; Asymmetric synthesis;

D O I：

10.1016/j.tet.2008.10.032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The martinelline chiral core 3 and its disastereomer were synthesized by using the asymmetric tandem Michael-aldol reaction as the key step from 4-methyoxycarbonylanthranilaldehyde and the alpha,beta-unsatuarated aldehyde (C) 2008 Published by Elsevier Ltd.

引用

页码：11568 / 11579

页数：12

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