Spinal Cord: Motor Neuron Diseases

被引：15

作者：

Rezania, Kourosh ^{[1
]}

Roos, Raymond P. ^{[1
]}

机构：

[1] Univ Chicago, Dept Neurol, Med Ctr, Chicago, IL 60637 USA

来源：

NEUROLOGIC CLINICS | 2013年 / 31卷 / 01期

关键词：

Motor neuron diseases; Amyotrophic lateral sclerosis; Spinal cord; Familial amyotrophic lateral sclerosis; AMYOTROPHIC-LATERAL-SCLEROSIS; BULBAR MUSCULAR-ATROPHY; FRONTOTEMPORAL LOBAR DEGENERATION; QUALITY STANDARDS SUBCOMMITTEE; CREUTZFELDT-JAKOB-DISEASE; PRACTICE PARAMETER UPDATE; ANDROGEN RECEPTOR GENE; CLINICAL CHARACTERISTICS; HEXANUCLEOTIDE REPEAT; RESPIRATORY-FAILURE;

D O I：

10.1016/j.ncl.2012.09.014

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Spinal cord motor neuron diseases affect lower motor neurons in the ventral horn. This article focuses on the most common spinal cord motor neuron disease, amyotrophic lateral sclerosis, which also affects upper motor neurons. Also discussed are other motor neuron diseases that only affect the lower motor neurons. Despite the identification of several genes associated with familial amyotrophic lateral sclerosis, the pathogenesis of this complex disease remains elusive.

引用

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页码：219 / +

页数：22

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