Synchronous adenocarcinoma and carcinoid tumor of the terminal ileum in a Crohn's disease patient

被引:21
作者
Cioffi, U [1 ]
De Simone, M
Ferrero, S
Ciulla, MM
Lemos, A
Avesani, EC
机构
[1] Univ Milan, Dept Surg, Fdn Osped Maggiore Policlin Mangiagalli & Regina, IRCCS, Milan, Italy
[2] Azienda Osped San Paolo, Dept Pathol, Milan, Italy
[3] Univ Milan, Ist Med Cardiovasc, Fdn Osped Maggiore Policlin Mangiagalli & Regina, IRCCS, Milan, Italy
[4] Univ Milan, Dept Radiol, Fdn Osped Maggiore Policlin Mangiagalli & Regina, IRCCS, Milan, Italy
关键词
D O I
10.1186/1471-2407-5-157
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Several malignancies have been described in association with inflammatory bowel diseases, the most common being adenocarcinoma. Carcinoid tumor and Crohn disease has also been previously reported, however the coexistence of both neoplasms is quite rare and the clinical diagnosis is very difficult. Here we report what we believe to be the fourth case of a mixed adenocarcinoid tumor coexisting with Crohn's disease. Case report: The patient presented with clinical and radiological features of intestinal obstruction. Laparotomy showed a stricturing lesion in the last 6 cm of the terminal ileum with proximal dilation. Only the histology of the resected surgical specimen proved the presence of a mixed adenocarcinoid tumor involving the terminal ileum. Conclusion: Carcinoid tumor should be suspected in elderly patients with Crohn's disease presenting with intestinal obstruction and laparotomy should be considered to exclude malignancy.
引用
收藏
页数:4
相关论文
共 10 条
[1]   Mixed adenocarcinoid tumor and Crohn's disease [J].
Auber, F ;
Gambiez, L ;
Desreumaux, P ;
Mudry, J ;
Lecomte-Houcke, M ;
Cortot, A ;
Quandalle, P ;
Colombel, JF .
JOURNAL OF CLINICAL GASTROENTEROLOGY, 1998, 26 (04) :353-354
[2]   Synchronous ileal and colonic adenocarcinomas associated with Crohn's disease: report of a case with a focus on genetic alterations and carcinogenesis [J].
Baisse, B ;
Fontolliet, C ;
Bian, YS ;
Vuilleumier, H ;
Benhattar, J .
JOURNAL OF CLINICAL PATHOLOGY, 2004, 57 (08) :885-887
[3]   Carcinoid tumour of the terminal ileum simulating Crohn disease [J].
Bassi, A ;
Loughran, C ;
Foster, P .
SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, 2003, 38 (09) :1004-1006
[4]   MIXED ADENOCARCINOMA CARCINOID-TUMOR OF LARGE-BOWEL IN A PATIENT WITH CROHNS-DISEASE [J].
HOCK, YL ;
SCOTT, KWM ;
GRACE, RH .
JOURNAL OF CLINICAL PATHOLOGY, 1993, 46 (02) :183-185
[5]  
Hsu EY, 1997, AM J GASTROENTEROL, V92, P2062
[6]   CARCINOID-TUMORS AND INFLAMMATORY BOWEL-DISEASE [J].
KORTBEEK, J ;
KELLY, JK ;
PRESHAW, RM .
JOURNAL OF SURGICAL ONCOLOGY, 1992, 49 (02) :122-126
[7]   Crohn's disease and cancer risk (Denmark) [J].
Mellemkjær, L ;
Johansen, C ;
Gridley, G ;
Linet, MS ;
Kjær, SK ;
Olsen, JH .
CANCER CAUSES & CONTROL, 2000, 11 (02) :145-150
[8]   GASTROINTESTINAL MALIGNANCIES IN CROHNS-DISEASE A 20-YEAR EXPERIENCE [J].
SAVOCA, PE ;
BALLANTYNE, GH ;
CAHOW, CE .
DISEASES OF THE COLON & RECTUM, 1990, 33 (01) :7-11
[9]   Small intestinal adenocarcinoma in Crohn's disease - A case-control study [J].
Solem, CA ;
Harmsen, WS ;
Zinsmeister, AR ;
Loftus, EV .
INFLAMMATORY BOWEL DISEASES, 2004, 10 (01) :32-35
[10]   COEXISTING CARCINOID-TUMOR AND CROHNS-DISEASE [J].
VANLANDINGHAM, SB ;
KLUPPEL, S ;
SYMMONDS, R ;
SNYDER, SK .
JOURNAL OF SURGICAL ONCOLOGY, 1983, 24 (04) :310-314