Synthesis and crystal structure of triethylammonium 5-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)(methylthio)methyl]-1,3-dimethylpyrimidine-2,4,6-trionate

被引：6

作者：

Al-Sheikh, Ahmad ^{[1
]}

Sweidanb, Kamal ^{[2
]}

Sweileh, Bassarn ^{[3
]}

Steimann, Manfred ^{[4
]}

Schubert, Hartmut ^{[4
]}

Kuhn, Norbert ^{[4
]}

机构：

[1] Petra Univ, Fac Pharm, Amman, Jordan

[2] Al Zaytoonah Univ Jordan, Fac Pharm, Amman, Jordan

[3] Univ Jordan, Dept Chem, Amman, Jordan

[4] Univ Tubingen, Inst Anorgan Chem, D-72076 Tubingen, Germany

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2008年 / 63卷 / 08期

关键词：

Meldrum's acid; 1,3-dimethylbarbitric acid; heterocycles; crystal structure;

D O I：

10.1515/znb-2008-0817

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Triethylammonium 5-[(2 2-dimethyl-4,6-dioxo-1,3-dioxan-5-ylidene)(methylthio)methyl]-1,3-dimethylpyrimidine-2,4,6-trionate (6) is obtained as red-orange stable crystals by reaction of 5-[bis(methylthio)methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione (5) with 1,3-dimethylbarbituric acid (2) in the presence of triethylamine in excellent yield. The crystal structure of 6 confirms the negative charge to be localized at the barbituric-acid ring in its enolate form.

引用

页码：1020 / 1022

页数：3

共 11 条

[1] Novel synthesis of barbiturates [J].