Depression and cardiovascular disease

被引:102
作者
Bradley, Steven M. [1 ,2 ,3 ]
Rumsfeld, John S. [1 ,2 ,3 ]
机构
[1] VA Eastern Colorado Hlth Care Syst, Dept Vet Affairs, Denver, CO 80220 USA
[2] Univ Colorado, Sch Med, Div Cardiol, Dept Med, Aurora, CO USA
[3] Colorado Cardiovasc Outcomes Res Consortium, Denver, CO USA
关键词
CORONARY-HEART-DISEASE; QUALITY-OF-LIFE; URINARY NOREPINEPHRINE EXCRETION; SEROTONIN REUPTAKE INHIBITORS; COLLABORATIVE CARE; RATE-VARIABILITY; ARTERY-DISEASE; RISK-FACTOR; MYOCARDIAL-INFARCTION; MAJOR DEPRESSION;
D O I
10.1016/j.tcm.2015.02.002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There is a wealth of evidence linking depression to increased risk for cardiovascular disease (CVD) and worse outcomes among patients with known CVD. In addition, there are safe and effective treatments for depression. Despite this, depression remains under-recognized and undertreated in patients at risk for or living with CVD. In this review, we first summarize the evidence linking depression to increased risk of CVD and worse patient outcomes. We then review the mechanisms by which depression may contribute to cardiovascular risk and poor cardiovascular outcomes. We then summarize prior studies of depression treatment on cardiovascular outcomes. Finally, we offer guidance in the identification and management of depression among CVD populations. Given that 1 in 4 CVD patients has concurrent depression, application of these best-practices will assist providers in achieving optimal outcomes for their CVD patients. Published by Elsevier Inc.
引用
收藏
页码:614 / 622
页数:9
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