Cellular Therapy for Treatment of Stress Urinary Incontinence

被引：12
|
作者：
Stangel-Wojcikiewicz, Klaudia [2 ]
Malgorzata, Stec [3 ]
Nikolavsky, Dmitriy [4 ]
Chancellor, Michael B. [1 ]
机构：
[1] Oakland Univ, William Beaumont Sch Med, Dept Urol, Royal Oak, MI 48073 USA
[2] Jagiellonian Univ Krakow, Coll Med, Dept Gynecol & Oncol, Krakow, Poland
[3] Jagiellonian Univ Krakow, Coll Med, Dept Transplantol, Krakow, Poland
[4] William Beaumont Hosp, Dept Urol, Royal Oak, MI 48072 USA
来源：
CURRENT STEM CELL RESEARCH & THERAPY | 2010年 / 5卷 / 01期
关键词：
Stress urinary incontinence; urethra; stem cell therapy;
D O I：
10.2174/157488810790442840
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
A critical mechanism to maintain urinary continence in women and men is the striated muscle sphincter (rhabdosphincter) that forms a ring around the mid urethra. Cellular therapy and the use of stem cells transplanted into the site of the rhabdosphincter in a setting of stress urinary incontinence may augment sphincter regeneration. Implanted cells may also release trophic factors promoting muscle and nerve integration into this muscle. We hereby review the use of cellular therapy for SUI and our experience with the development of muscle-derived stem cells.
引用
收藏
页码：57 / 62
页数：6
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