Rapid microwave-promoted synthesis of new sulfonylmethylbenzothiazoles in water

被引：43

作者：

Gellis, A ^{[1
]}

Boufatah, N ^{[1
]}

Vanelle, P ^{[1
]}

机构：

[1] Univ Mediterranee, Fac Pharm, CNRS, UMR 6517,LCOP, F-13385 Marseille 5, France

来源：

GREEN CHEMISTRY | 2006年 / 8卷 / 05期

关键词：

D O I：

10.1039/b601452f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A simple, fast and inexpensive microwave- irradiated reaction permitting the synthesis of new sulfonylmethylbenzothiazoles in water by S-alkylation of 2-chloromethyl-6-nitrobenzothiazole 2 with different benzenesulfinic acid anions 3 is reported.

引用

页码：483 / 487

页数：5

共 24 条

[1] Rapid microwave-promoted Suzuki cross coupling reaction in water [J].

Bai, L ;

Wang, JX ;

Zhang, YM .

GREEN CHEMISTRY, 2003, 5 (05) :615-617

[2] Microwave assisted synthesis of an unusual dinitro phytochemical [J].

Bose, AK ;

Ganguly, SN ;

Manhas, MS ;

Srirajan, V ;

Bhattacharjee, A ;

Rumthao, S ;

Sharma, AH .

TETRAHEDRON LETTERS, 2004, 45 (06) :1179-1181

[3] 2-(4-aminophenyl)benzothiazoles: novel agents with selective profiles of in vitro anti-tumour activity [J].

Bradshaw, TD ;

Wrigley, S ;

Shi, DF ;

Schultz, RJ ;

Paull, KD ;

Stevens, MFG .

BRITISH JOURNAL OF CANCER, 1998, 77 (05) :745-752

[4] Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles [J].

Garuti, L ;

Roberti, M ;

De Clercq, E .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2002, 12 (19) :2707-2710

[5] SOME CHAIN-SUBSTITUTED METHINCYANINES AND STYRYL DYES [J].

HAMER, FM .

JOURNAL OF THE CHEMICAL SOCIETY, 1956, (JUN) :1480-1498

[6] Antitumour benzothiazoles.: Part 20:: 3′-cyano and 3′-alkynyl-substituted 2-(4′-aminophenyl)benzothiazoles as new potent and selective analogues [J].

Hutchinson, I ;

Bradshaw, TD ;

Matthews, CS ;

Stevens, MFG ;

Westwell, AD .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (03) :471-474

[7] Antitumor benzothiazoles. 16. Synthesis and pharmaceutical properties of antitumor 2-(4-aminophenyl)benzothiazole amino acid prodrugs [J].

Hutchinson, I ;

Jennings, SA ;

Vishnuvajjala, BR ;

Westwell, AD ;

Stevens, MFG .

JOURNAL OF MEDICINAL CHEMISTRY, 2002, 45 (03) :744-747

[8] Antitumor benzothiazoles. 14. Synthesis and in vitro biological properties of fluorinated 2-(4-aminophenyl)benzothiazoles [J].

Hutchinson, I ;

Chua, MS ;

Browne, HL ;

Trapani, V ;

Bradshaw, TD ;

Westwell, AD ;

Stevens, MFG .

JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (09) :1446-1455

[9] Controlled microwave heating in modern organic synthesis [J].

Kappe, CO .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (46) :6250-6284

[10]

Kocí J, 2002, BIOORG MED CHEM LETT, V12, P3275

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