Thymoma and Thymic Carcinoma Arising in a Thymolipoma: Report of a Unique Case

被引：10

作者：

Haddad, Hussam ^{[1
]}

Joudeh, Amani ^{[1
]}

El-Taani, Hani ^{[2
]}

Mansour, Asem

Morcos, Basem ^{[3
]}

Fayoumi, Said ^{[3
]}

Sughayer, Maher ^{[1
]}

机构：

[1] King Hussein Canc Ctr, Dept Pathol, Amman, Jordan

[2] King Hussein Canc Ctr, Dept Med, Amman, Jordan

[3] King Hussein Canc Ctr, Dept Surg, Amman, Jordan

来源：

INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY | 2009年 / 17卷 / 01期

关键词：

thymic carcinoma; thymolipoma; thymoma; immunostains;

D O I：

10.1177/1066896908315822

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Thymic carcinoma arising within a thymolipoma has not been reported previously. The authors present a unique case of thymoma and undifferentiated thymic carcinoma arising within a thymolipoma in a 36-year-old woman. The of the resected mass was composed of benign fatty tissue admixed with foci of unremarkable thymic tissue; however, it also harbored a central solid Mass showing undifferentiated thymic carcinoma associated with a type 132 thymoma. The carcinoma cells were positive for cytokeratin AE1/AE3, cytokeratin 19, and cytokeratin 8/18. They were negative for vimentin, cytokeratin 7, cytokeratin 20, CD5, epithelial membrane antigen, CD30, placental alkaline phosphatase, carcinoembryonic antigen, CD99, leukocyte common antigen, Epstein-Barr virus, inhibin alpha, mid protein gene product 9.5. Hare tumor cells showed positive staining for chromogranin and synaptophysin.

引用

页码：55 / 59

页数：5

共 12 条

[1] THYMOLIPOMA SIMULATING CARDIOMEGALY - CLINICOPATHOLOGICAL RARITY [J].