Pulsatile blood flow in a resistance vessel

被引:0
作者
Shadrina, N. Kh. [1 ]
机构
[1] Russian Acad Sci, IP Pavlov Physiol Inst, St Petersburg, Russia
关键词
blood vessel; blood flow; properties of the active vessel; nitric oxide diffusion; pulsatile flow; amplitude and frequency dependence; NITRIC-OXIDE; PRESSURE; TUBES;
D O I
10.1134/S0015462812060075
中图分类号
O3 [力学];
学科分类号
08 ; 0801 ;
摘要
The quasi-one-dimensional Newtonian fluid flow in an active vessel in which the inlet pressure oscillates about a mean value is considered. The vascular wall is assumed to display the Bayliss effect and a reaction to changes in blood flow. The first is characterized by the dependence of the contractility of the vascular smooth-muscle cells on the intravascular pressure and the second by the sensitivity of the endothelial cells to the wall shear stress. The dependence of the period-average radius and blood flow rate on the mean value and pulsation amplitude and frequency of the inlet pressure is investigated numerically. The characteristics are compared for the passive vessel, the vessel with the Bayliss effect, and the vessel with both reactions.
引用
收藏
页码:748 / 757
页数:10
相关论文
共 26 条
[1]  
Aletti Federico, 2009, Nonlinear Biomed Phys, V3, P7, DOI 10.1186/1753-4631-3-7
[2]   Modeling arteriolar flow and mass transport using the immersed boundary method [J].
Arthurs, KM ;
Moore, LC ;
Peskin, CS ;
Pitman, EB ;
Layton, HE .
JOURNAL OF COMPUTATIONAL PHYSICS, 1998, 147 (02) :402-440
[3]   Regulation of blood flow in the microcirculation: role of conducted vasodilation [J].
Bagher, P. ;
Segal, S. S. .
ACTA PHYSIOLOGICA, 2011, 202 (03) :271-284
[4]   Regulation of the lumen of a resistance blood vessel by mechanical stimuli [J].
Buchin, V. A. ;
Shadrina, N. Kh. .
FLUID DYNAMICS, 2010, 45 (02) :211-222
[5]   NITRIC-OXIDE MEDIATES FLOW-DEPENDENT EPICARDIAL CORONARY VASODILATION TO CHANGES IN PULSE FREQUENCY BUT NOT MEAN FLOW IN CONSCIOUS DOGS [J].
CANTY, JM ;
SCHWARTZ, JS .
CIRCULATION, 1994, 89 (01) :375-384
[6]  
Dvoretskii J.P., 1991, MODERN PROBLEMS BIOM, V8, P53
[7]  
Dvoretskii J.P., 1993, FIZIOL ZH SSSR IM I, V79, P50
[8]  
Egorov V. A., 1994, Fluid Dynamics, V29, P221, DOI 10.1007/BF02324311
[9]   Modelling of pulsatile blood flow in arterial trees of retinal vasculature [J].
Ganesan, P. ;
He, S. ;
Xu, H. .
MEDICAL ENGINEERING & PHYSICS, 2011, 33 (07) :810-823
[10]   What is the real physiological NO concentration in vivo? [J].
Hall, Catherine N. ;
Garthwaite, John .
NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2009, 21 (02) :92-103