The evolutionary biography of chronic lymphocytic leukemia

被引:36
作者
Puente, Xose S. [1 ,2 ]
Lopez-Otin, Carlos [1 ,2 ]
机构
[1] Univ Oviedo, Dept Bioquim & Biol Mol, Oviedo, Spain
[2] Univ Oviedo, Inst Univ Oncol IUOPA, Oviedo, Spain
关键词
CLONAL EVOLUTION;
D O I
10.1038/ng.2556
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A recent study shows that the life history of chronic lymphocytic leukemia is characterized by a complex and dynamic architecture involving the development of subclones with changing dominance over time. This innovative study provides a framework to design anticipation-based chemotherapy approaches for cancer treatment.
引用
收藏
页码:229 / 231
页数:3
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