Update on Herpes simplex keratitis management

被引：41

作者：

Sibley, Daniel ^{[1
]}

Larkin, Daniel F. P. ^{[1
,2
,3
]}

机构：

[1] Moorfields Eye Hosp, Cornea & External Dis Serv, 162 City Rd, London EC1V 2PD, England

[2] Moorfields Eye Hosp, NIHR Moorfields Clin Res Facil, London, England

[3] UCL Inst Ophthalmol, London, England

来源：

EYE | 2020年 / 34卷 / 12期

关键词：

HELICASE-PRIMASE INHIBITOR; ORAL ACYCLOVIR ZOVIRAX; VIRUS EYE DISEASE; STROMAL KERATITIS; CORNEAL NEOVASCULARIZATION; PHARMACOKINETICS; TYPE-1; EPIDEMIOLOGY; BEVACIZUMAB; PREVENTION;

D O I：

10.1038/s41433-020-01153-x

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Herpes simplex keratitis (HSK) is a common, potentially blinding condition characterised by recurrent infections of the cornea, seen by both general ophthalmologists and corneal specialists. Successful treatment of recurrences reduces disease duration, prevents progressive corneal scaring leading to vision loss and reduces risk of further recurrences. In this review we discuss the relative advantages of the diagnostic laboratory investigations including polymerase chain reaction, viral culture and fluorescence-based immunohistochemistry. We review treatment strategies in selected aspects of HSK and discuss the management options in cases not responding to treatment.

引用

页码：2219 / 2226

页数：8

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