Changes in lipid density induce membrane curvature

被引：8
|
作者：
de Jesus, Armando J.
Kastelowitz, Noah
Yin, Hang [1 ]
机构：
[1] Univ Colorado, Dept Chem & Biochem, Boulder, CO 80303 USA
来源：
RSC ADVANCES | 2013年 / 3卷 / 33期
基金：
美国国家科学基金会; 美国国家卫生研究院;
关键词：
MOLECULAR-DYNAMICS SIMULATIONS; BAR DOMAINS; LYSOLIPIDS; FLIPPASES; PROTEINS; BILAYER; VESICLE;
D O I：
10.1039/c3ra42332h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Highly curved bilayer lipid membranes make up the shell of many intra- and extracellular compartments, including organelles and vesicles. Using all-atom molecular dynamics simulations, we show that increasing the density of lipids in the bilayer membrane can induce the membrane to form a curved shape.
引用
收藏
页码：13622 / 13625
页数：4
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