Two-domain DNA strand displacement

被引:75
|
作者
Cardelli, Luca [1 ]
机构
[1] Microsoft Res, Cambridge CB3 0FB, England
关键词
D O I
10.1017/S0960129512000102
中图分类号
TP301 [理论、方法];
学科分类号
081202 ;
摘要
We investigate the computing power of a restricted class of DNA strand displacement structures: those that are made of double strands with nicks (interruptions) in the top strand. To preserve this structural invariant, we impose restrictions on the single strands they interact with: we consider only two-domain single strands consisting of one toehold domain and one recognition domain. We study fork and join signal processing gates based on these structures, and show that these systems are amenable to formalisation and mechanical verification.
引用
收藏
页码:247 / 271
页数:25
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