Oral ivermectin in the treatment of body lice

被引：50

作者：

Foucault, C ^{[1
]}

Ranque, S ^{[1
]}

Badiaga, S ^{[1
]}

Rovery, C ^{[1
]}

Raoult, D ^{[1
]}

Brouqui, P ^{[1
]}

机构：

[1] Univ Mediterranee, Unite Rickettsies, CNRS, UMR 6020,Lab Parasitol Mycol,INSERM,UMR 399, F-13385 Marseille 05, France

来源：

JOURNAL OF INFECTIOUS DISEASES | 2006年 / 193卷 / 03期

关键词：

D O I：

10.1086/499279

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The mainstays of treatment of body-louse infestation in humans in a community setting are insecticides and the removal of infested clothing. We report here the dramatic effect that 3 doses of oral ivermectin ( 12 mg each), administered at 7-day intervals, have in reducing the total number of body lice in a cohort of homeless men from a shelter in Marseilles, France. We identified a baseline total of 1898 lice in the cohort. Over a 14-day period, this number fell to 6 lice; the prevalence of infested individuals fell from 84.9% to 18.5%. Although this effect was not sustained at day 45, it establishes that ivermectin plays a novel role in the control of body-louse infestation in humans.

引用

页码：474 / 476

页数：3

共 5 条

[1] Treatment of Pediculus humanus var. Capitis infestation in Cowlitz County, Washington, with ivermectin and the LiceMeister® comb [J].