Oropharyngeal candidiasis prevalence among HIV-infected patients at the teaching hospital of Treichville (Abidjan, Cote d'Ivoire)

被引:8
作者
Konate, A. [1 ,3 ]
Barro-Kiki, P. C. M. [1 ]
Kassi, K. F. [1 ,2 ]
Angora, K. E. [1 ]
Vanga-Bosson, H. [1 ]
Djohan, V. [1 ]
Bedia-Tanoh, A. V. [1 ]
Miezan, A. J. S. [1 ]
Yavo, W. [1 ]
Menan, E. I. H. [1 ,2 ]
机构
[1] Felix Houphouet Boigny Univ, Dept Parasitol Mycol Anim Biol & Zool, BPV 34, Abidjan, Cote Ivoire
[2] Diag & Res Ctr AIDS & Others Infect Dis, Lab Parasitol & Mycol, 01 BPV 13, Abidjan, Cote Ivoire
[3] Teaching Hosp Yopougon, Lab Parasitol & Mycol, 21 BP 632, Abidjan 21, Cote Ivoire
来源
JOURNAL DE MYCOLOGIE MEDICALE | 2017年 / 27卷 / 04期
关键词
Oropharyngeal candidiasis; Risk factors; Candida; Cote d'Ivoire; POSITIVE PATIENTS; DUBLINIENSIS; ALBICANS; FLUCONAZOLE; COLONIZATION; RESISTANCE; GLABRATA; AFRICANA;
D O I
10.1016/j.mycmed.2017.08.005
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Aim of the study. - The aim of this study was to determine the mycological profile of oropharyngeal candidiasis among HIV-infected patients from Internal Medicine, Infectious and Tropical Diseases, and Pneumo-Phthisiology Diseases departments of the Teaching Hospital of Treichville in Abidjan, Cote d'Ivoire. Patients and methods. - This was a cross-sectional study carried out on patients with lesions suggestive of oropharyngeal candidiasis from October 2010 to April 2011. Oral swabs were cultured, and Candida species were identified using a germ tube test, a chlamydospore formation assay, and the API 20C system. Results. - A total of 286 patients were included, among whom 99.1% were infected with HIV. The prevalence of oropharyngeal candidiasis was 79.4% (CI95% = 74.4-83.8). Five different species of Candida were identified, with the predominant species being Candida albicans (95.2%). Most affected patients were female (54.6%, P < 0.0001) between the ages of 30 and 45 (78.4%, P < 0.0001). The most lesion types observed were thrush (87.8%). Patients infected with HIV1 (95.6%), with a primary school level of education (52.8%), under antiretroviral therapy (88.5%) and with tuberculosis as an associated pathology (62.5%) were the most commonly affected. Patients were mostly under ART first line treatment (86.4%) and at the beginning of the treatment (86.4%). Conclusion. - Oropharyngeal candidiasis is frequent among HIV-infected patients. Better and early management of this vulnerable population should allow for a reduction in the high prevalence observed. (C) 2017 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:549 / 553
页数:5
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