Anticancer Activity and Chemical Composition of Leaf Essential Oil from Solidago canadensis L. in China

被引：13
|
作者：
Li, Deqiang [1 ]
Pan, Shenghao [1 ]
Zhu, Xiwu [1 ]
Tan, Lin [1 ]
Cao, Yuefen [1 ]
机构：
[1] Zhejiang Sci Tech Univ, Inst Bioengn, Hangzhou, Zhejiang, Peoples R China
来源：
RENEWABLE AND SUSTAINABLE ENERGY, PTS 1-7 | 2012年 / 347-353卷
关键词：
Solidago canadensis; compositae; essential oil composition; (-)germacrene D; anticancer activity; CONSTITUENTS; ASTERACEAE;
D O I：
10.4028/www.scientific.net/AMR.347-353.1584
中图分类号：
TE [石油、天然气工业]; TK [能源与动力工程];
学科分类号：
0807 ; 0820 ;
摘要：
The essential oil was obtained at yield of 0.30% by hydrodistillation from fresh leaf tissue of Solidago canadensis L. collected from Zhejiang Province, China. GC and GC/MS analysis identified 46 components, representing 94.6% of the leaf oil. The main components were (-)germacrene D (28.4%), bornyl acetate (9.2%), D-Limonene (5.0%). The essential oil was tested for cytotoxic activities against three tumor cell lines. The inhibitory concentrations of the essential oil at 50% effect level (IC50) were 68.1 mu g/ml for SMMC-7721, 71.4 mu g/ml for SGC-7901, and 156.9 mu g/ml for Hala, respectively.
引用
收藏
页码：1584 / 1589
页数：6
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