A New Series of Sorbent Devices for Multiple Clinical Purposes: Current Evidence and Future Directions

被引：85

作者：

Ankawi, Ghada ^{[1
,2
,3
]}

Fan, Weixuan ^{[1
,4
]}

Montin, Diego Pomare ^{[1
]}

Lorenzin, Anna ^{[1
,5
]}

Neri, Mauro ^{[1
,5
]}

Caprara, Carlotta ^{[1
,6
]}

de Cal, Massimo ^{[5
]}

Ronco, Claudio ^{[1
,5
]}

机构：

[1] IRRIV, Vicenza, Italy

[2] King Abdulaziz Univ, Dept Internal Med, Jeddah, Saudi Arabia

[3] King Abdulaziz Univ, Dept Nephrol, Jeddah, Saudi Arabia

[4] Jilin Univ, Hosp 2, Dept Emergency & Crit Care Med, Changchun, Jilin, Peoples R China

[5] San Bortolo Hosp, Dept Nephrol Dialysis & Transplant, Vicenza, Italy

[6] Ist Ric Pediat, Citta Speranza, Lab Genet Clin & Epidemiol, Padua, Italy

来源：

BLOOD PURIFICATION | 2019年 / 47卷 / 1-3期

关键词：

Endotoxin; Extracorporeal therapy; Adsorption; Sepsis; Uremia; Intoxication; Sorbents; HEMOPERFUSION;

D O I：

10.1159/000493523

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adsorption is an extracorporeal technique utilized for blood purification. It complements convection and diffusion (the main modalities of solute removal). It involves the passage of blood (or plasma) through an adsorption cartridge, where solutes are removed by direct binding to the sorbent material. Over the years, new adsorption cartridges, with improved characteristics have been developed. Furthermore, the therapeutic applications of adsorption have expanded. These now involve the treatment of inflammatory conditions, chronic uremic symptoms, and autoimmune disease, in addition to intoxication, which was once considered the classical indication for adsorption therapy. HA130, HA230, and HA330 (Jafron, Zhuhai City, China) are among the widely used adsorption cartridges in China. There has been sufficient body of evidence to support their effectiveness and safety. In this review, we aim to highlight their main clinical applications. (c) 2018 The Author(s) Published by S. Karger AG, Basel

引用

页码：94 / 100

页数：7

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