Isolation of Chalcones from the Root of Codonopsis cordifolioidea and Their Antitobacco Mosaic Virus Activities

被引：2
作者：
Meng, Chun-Yang [1 ,2 ,3 ]
Han, Yi [3 ]
Duan, Yuan-Xing [3 ]
Chen, Jin-Xiong [3 ]
Hu, Qiu-Fen [1 ,2 ]
Gao, Xue-Mei [1 ,2 ]
机构：
[1] Yunnan Univ Nationalities, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China
[2] Yunnan Univ Nationalities, Minist Educ, Kunming 650031, Peoples R China
[3] Yunnan Acad Tobacco Sci, Key Lab Tobacco Chem Yunnan Prov, Kunming 650106, Peoples R China
来源：
ASIAN JOURNAL OF CHEMISTRY | 2013年 / 25卷 / 17期
关键词：
Chalcone; Codonopsis cordifolioidea; Antitobacco mosaic virus activities; CONSTITUENTS; LEAVES;
D O I：
10.14233/ajchem.2013.15052A
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new chalcone, 4'-acetoxy-5-hydroxy-6-methoxy-chalcone (1) and four known chalcones (2-5) were isolated from the roots of Codonopsis cordifolioidea. Their structures were elucidated by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1-5 were tested for their antitobacco mosaic virus activities. Compounds 1 (20 mu M) showed moderate anti tobacco mosaic virus activity with inhibition rates of 18.2 %. Compounds 2-5 showed low anti tobacco mosaic virus activities with inhibitory rates below 10 %.
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收藏
页码：9517 / 9519
页数：3
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