Recent developments in Pickering emulsions for biomedical applications

被引:152
作者
Harman, Clarissa L. G. [1 ,2 ]
Patel, Mehzabin A. [2 ]
Guldin, Stefan [2 ]
Davies, Gemma-Louise [1 ]
机构
[1] UCL, Dept Chem, 20 Gordon St, London WC1H 0AJ, England
[2] UCL, Dept Chem Engn, Torrington Pl, London WC1E 7JE, England
基金
英国工程与自然科学研究理事会;
关键词
Pickering emulsions; Biomedicine; Stimuli-responsive; Therapeutic delivery; OIL-IN-WATER; SILICA NANOPARTICLES; TOPICAL APPLICATION; PANCREATIC-CANCER; PH; LIGHT; PARTICLES; DELIVERY; EMULSIFIERS; COALESCENCE;
D O I
10.1016/j.cocis.2019.01.017
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Pickering emulsions, stabilised by organic or inorganic particles, offer long-term dispersibility of liquid droplets and resistance to coalescence. The versatility of stabilising particles and their ability to encapsulate and release cargo with high internal payload capacity makes them attractive in a wide variety of applications, ranging from catalysis to the cosmetic and food industry, While these properties make them an equally promising material platform for pharmaceutical and clinical applications, the development of Pickering emulsions for healthcare is still in its infancy. Herein, we summarise and discuss recent progress in the development of Pickering emulsions for biomedical applications, probing their design for passive diffusion-based release as well as stimuli-responsive destabilisation. We further comment on challenges and future directions of this exciting and rapidly expanding area of research.
引用
收藏
页码:173 / 189
页数:17
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