α-Arylation, α-Arylative Esterification, or Acylation: A Stoichiometry-Dependent Trichotomy in the Pd-Catalyzed Cross-Coupling between Aldehydes and Aryl Bromides

被引：9

作者：

Nareddy, Pradeep ^{[1
]}

Mazet, Clement ^{[1
]}

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2013年 / 8卷 / 11期

基金：

瑞士国家科学基金会;

关键词：

acylation; arylation; cross-coupling; esterification; palladium; HETEROCYCLIC CARBENE LIGANDS; ENANTIOSELECTIVE SYNTHESIS; (NHC)PD(ALLYL)CL NHC; RATE ACCELERATION; TERMINAL ALKYNES; ACYL CHLORIDES; HETISINE-TYPE; A-ARYLATION; PALLADIUM; KETONES;

D O I：

10.1002/asia.201300724

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three′s company: The selective α-arylation and α-arylative esterification of linear and branched aldehydes is reported for a variety of bromoarenes. The acylation of aryl bromides can be achieved with linear aldehydes (see scheme). All these transformations were performed with a single [(N-heterocyclic carbene)Pd] catalyst through adjustment of the stoichiometry of the reagents and the appropriate base. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：2579 / 2583

页数：5

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