A New Method for the Benzylic Oxidation of Alkylarenes Catalyzed by Hypervalent Iodine(III)

被引：21

作者：

Xu, Yuan ^{[1
]}

Yang, Zhenping ^{[1
]}

Hu, Jiantao ^{[1
]}

Yan, Jie ^{[1
]}

机构：

[1] Zhejiang Univ Technol, Coll Chem Engn & Mat Sci, Hangzhou 310032, Zhejiang, Peoples R China

来源：

SYNTHESIS-STUTTGART | 2013年 / 45卷 / 03期

关键词：

benzylic oxidations; hypervalent iodine reagent; (diacetoxyiodo)benzene; ketones; SELECTIVE OXIDATION; TERT; GENERATION; SYSTEM; DEPROTECTION; ALCOHOLS; REAGENT; KETONES; ETHERS; ACID;

D O I：

10.1055/s-0032-1316838

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and simple procedure is described for the oxidation of the benzylic C-H moiety of alkylarenes to give the corresponding aryl ketones, using tert-butyl hydroperoxide and m-chloroperoxybenzoic acid in the presence of a catalytic amount of the hypervalent iodine reagent, (diacetoxyiodo)benzene. The reactions typically occur in good yields in 2,2,2-trifluoroethanol as the solvent and at room temperature.

引用

页码：370 / 374

页数：5

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