Novel therapeutic strategies for large vessel vasculitis

被引：13
作者：
Koening, CL [1 ]
Langford, CA [1 ]
机构：
[1] Cleveland Clin Fdn, Dept Rheumat & Immunol Dis, Ctr Vasculitis Care & Res, Cleveland, OH 44195 USA
来源：
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2006年 / 32卷 / 01期
关键词：
D O I：
10.1016/j.rdc.2005.09.006
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Giant cell arteritis and Takayasu's arteritis are systemic vasculitides that cause inflammation of large arteries and their branches. Both have similar histology, but differ in their age of onset. Corticosteroids have been the mainstay of treatment for the past 50 years but are limited by the potential toxicity that may occur in almost 60% of patients. This limitation has lead to the investigation of alternative agents for the treatment of these diseases.
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页码：173 / +
页数：15
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