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Silica Sulfuric Acid-Catalyzed One-Pot Synthesis, Mechanism, and Fluorescence Properties of 2-(2-arylquinolin-4-(1H)-ylidene)malononitriles
被引:1
作者:
Wan, Yu
[1
,2
]
Lin, Wei
[1
,2
]
Xin, Hai-qiang
[1
,2
]
Yuan, Rui
[1
,2
]
Zhao, Ling-ling
[1
,2
]
Shi, Jing-jing
[1
,2
]
Wang, Chao
[1
,2
]
Zhang, Xiao-xiao
[1
,2
]
Wu, Hui
[1
,2
]
机构:
[1] Xuzhou Normal Univ, Sch Chem & Chem Engn, Xuzhou 221116, Peoples R China
[2] Key Lab Biotechnol Med Plant Jiangsu Prov, Xuzhou 221116, Jiangsu, Peoples R China
关键词:
ANTIMITOTIC ANTITUMOR AGENTS;
NS3;
PROTEASE;
DERIVATIVES;
CYTOTOXICITY;
QUINOLONES;
INHIBITORS;
DISCOVERY;
REAGENTS;
TUBULIN;
ROUTE;
D O I:
10.1002/jhet.1577
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
A mild, one-pot synthesis of 2-(2-arylquinolin-4-(1H)-ylidene)malononitriles is developed via the silica sulfuric acid-catalyzed tandem condensation of 2-aminoacetophenone with malononitrile and aromatic aldehyde in ionic liquid. It is proposed that malononitrile acted as not only a reactant but also a promoter in the interesting process. The fluorescence properties screening showed a new compound has high fluorescence quantum yield.
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页码:844 / 849
页数:6
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