Silica Sulfuric Acid-Catalyzed One-Pot Synthesis, Mechanism, and Fluorescence Properties of 2-(2-arylquinolin-4-(1H)-ylidene)malononitriles

被引:1
作者
Wan, Yu [1 ,2 ]
Lin, Wei [1 ,2 ]
Xin, Hai-qiang [1 ,2 ]
Yuan, Rui [1 ,2 ]
Zhao, Ling-ling [1 ,2 ]
Shi, Jing-jing [1 ,2 ]
Wang, Chao [1 ,2 ]
Zhang, Xiao-xiao [1 ,2 ]
Wu, Hui [1 ,2 ]
机构
[1] Xuzhou Normal Univ, Sch Chem & Chem Engn, Xuzhou 221116, Peoples R China
[2] Key Lab Biotechnol Med Plant Jiangsu Prov, Xuzhou 221116, Jiangsu, Peoples R China
关键词
ANTIMITOTIC ANTITUMOR AGENTS; NS3; PROTEASE; DERIVATIVES; CYTOTOXICITY; QUINOLONES; INHIBITORS; DISCOVERY; REAGENTS; TUBULIN; ROUTE;
D O I
10.1002/jhet.1577
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A mild, one-pot synthesis of 2-(2-arylquinolin-4-(1H)-ylidene)malononitriles is developed via the silica sulfuric acid-catalyzed tandem condensation of 2-aminoacetophenone with malononitrile and aromatic aldehyde in ionic liquid. It is proposed that malononitrile acted as not only a reactant but also a promoter in the interesting process. The fluorescence properties screening showed a new compound has high fluorescence quantum yield.
引用
收藏
页码:844 / 849
页数:6
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