A case of childhood T cell acute lymphoblastic leukemia with a complex t(9;9) and homozygous deletion of CDKN2A gene associated with a Philadelphia-positive minor subclone

被引：4

作者：

Ney-Garcia, Daniela Ribeiro ^{[1
]}

Liehr, Thomas ^{[2
]}

Bhatt, Samarth ^{[2
]}

de Souza, Mariana Tavares ^{[1
]}

de Figueiredo, Amanda Faria ^{[1
]}

Ribeiro, Raul Correa ^{[3
,4
]}

Macedo Silva, Maria Luiza ^{[1
]}

机构：

[1] Inst Nacl Canc INCA, Ctr Transplante Medula Osseo CEMO, Lab Citogenet, BR-20230130 Rio De Janeiro, RJ, Brazil

[2] Univ Jena, Jena Univ Hosp, Inst Human Genet, D-07743 Jena, Germany

[3] St Jude Childrens Res Hosp, Dept Oncol, Memphis, TN 38105 USA

[4] St Jude Childrens Res Hosp, Int Outreach Program, Memphis, TN 38105 USA

来源：

BLOOD CELLS MOLECULES AND DISEASES | 2013年 / 50卷 / 02期

关键词：

D O I：

10.1016/j.bcmd.2012.09.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：131 / 133

页数：3

共 6 条

[1] CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono- and bi-allelic 9p21 deletions in childhood acute lymphoblastic leukemia [J].

Bertin, R ;

Acquaviva, C ;

Mirebeau, D ;

Guidal-Giroux, C ;

Vilmer, E ;

Cavé, H .

GENES CHROMOSOMES & CANCER, 2003, 37 (01) :44-57

[2]

de Figueiredo A.F., 2012, LEUKEMIA RES, V36, P74

[3] Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast [J].

Graux, C. ;

Cools, J. ;

Michaux, L. ;

Vandenberghe, P. ;

Hagemeijer, A. .

LEUKEMIA, 2006, 20 (09) :1496-1510

[4] ABLI Rearrangements in T-Cell Acute Lymphoblastic Leukemia [J].

Hagemeijer, Anne ;

Graux, Carlos .

GENES CHROMOSOMES & CANCER, 2010, 49 (04) :299-308

[5] Presence of a minor Philadelphia-positive clone in young adults with de novo T-cell ALL [J].

Prebet, Thomas ;

Mozziconacci, Marie Joelle ;

Sainty, Danielle ;

Arnoulet, Christine ;

Lafage, Marina ;

Dastugue, Nicole ;

Charbonnier, Aude ;

Coso, Diane ;

Gastaut, Jean-Albert ;

Blaise, Didier ;

Vey, Norbert .

LEUKEMIA & LYMPHOMA, 2009, 50 (03) :485-487

[6] A comprehensive analysis of the CDKN2A gene in childhood acute lymphoblastic leukemia reveals genomic deletion, copy number neutral loss of heterozygosity, and association with specific cytogenetic subgroups [J].

Sulong, Sarina ;

Moorman, Anthony V. ;

Irving, Julie A. E. ;

Strefford, Jonathan C. ;

Konn, Zoe J. ;

Case, Marian C. ;

Minto, Lynne ;

Barber, Kerry E. ;

Parker, Helen ;

Wright, Sarah L. ;

Stewart, Adam R. M. ;

Bailey, Simon ;

Bown, Nick P. ;

Hall, Andrew G. ;

Harrison, Christine J. .

BLOOD, 2009, 113 (01) :100-107

← 1 →