Iodine-promoted silylation of alcohols with silyl chlorides. Synthetic and mechanistic studies

被引：24

作者：

Bartoszewicz, Agnieszka ^{[1
]}

Kalek, Marcin ^{[1
]}

Stawinski, Jacek ^{[1
,2
]}

机构：

[1] Stockholm Univ, Arrhenius Lab, Dept Organ Chem, S-10691 Stockholm, Sweden

[2] Polish Acad Sci, Inst Bioorgan Chem, PL-61704 Poznan, Poland

来源：

TETRAHEDRON | 2008年 / 64卷 / 37期

基金：

瑞典研究理事会;

关键词：

D O I：

10.1016/j.tet.2008.06.070

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient silylating system for 1 degrees, 2 degrees, and 3 degrees, alcohols, consisting of a silyl chloride/N-methylimidazole/iodine, was developed. Synthetic and mechanistic aspects of this new reagent system, and particularly the role of iodine were investigated in detail using H-1 NMR spectroscopy. (C) 2008 Elsevier Ltd. All rights reserved.

引用

页码：8843 / 8850

页数：8

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