Multifunctional carbon dots with high quantum yield for imaging and gene delivery

被引：208

作者：

Hu, Liming ^{[1
]}

Sun, Yun ^{[1
]}

Li, Shengliang ^{[2
]}

Wang, Xiaoli ^{[1
]}

Hu, Kelei ^{[2
]}

Wang, Lirong ^{[2
]}

Liang, Xing-jie ^{[2
]}

Wu, Yan ^{[2
]}

机构：

[1] Beijing Univ Technol, Coll Life Sci & Bioengn, Beijing 100124, Peoples R China

[2] Natl Ctr Nanosci & Technol, Beijing 100190, Peoples R China

来源：

CARBON | 2014年 / 67卷

基金：

中国国家自然科学基金;

关键词：

NANOPARTICLES; NANODOTS; POLYETHYLENIMINE; PYROLYSIS;

D O I：

10.1016/j.carbon.2013.10.023

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Carbon dots (CD) are luminescent nanomaterial with unique properties that show great potential in many applications. Herein, branched polyethyleneimine-based carbon dots (PCD) are prepared from branched polyethyleneimine by oxidation and a modified hydrothermal reaction. Structure and composition analysis indicate that obtained PCD possesses a 3-4 am in diameter and a graphitic structure with lattice spacing of 0.30 nm. The PCD has a quantum yield of 54.3%. The bright photoluminescence shows that it can be used for cell imaging. The PCD exhibits extremely good biocompatibility and can be applied for gene delivery. Because of its specific nanostructure and photoluminescence property the multifunctional PCD prepared shows potential for applications in bioimaging and gene delivery. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：508 / 513

页数：6

共 24 条

[1] Luminescent Carbon Nanodots: Emergent Nanolights [J].

Baker, Sheila N. ;

Baker, Gary A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2010, 49 (38) :6726-6744

[2] Electrochemical Tuning of Luminescent Carbon Nanodots: From Preparation to Luminescence Mechanism [J].

Bao, Lei ;

Zhang, Zhi-Ling ;

Tian, Zhi-Quan ;

Zhang, Li ;

Liu, Cui ;

Lin, Yi ;

Qi, Baoping ;

Pang, Dai-Wen .

ADVANCED MATERIALS, 2011, 23 (48) :5801-5806

[3] Isolation and characterization of fluorescent nanoparticles from pristine and oxidized electric arc-produced single-walled carbon nanotubes [J].

Bottini, M ;

Balasubramanian, C ;

Dawson, MI ;

Bergamaschi, A ;

Bellucci, S ;

Mustelin, T .

JOURNAL OF PHYSICAL CHEMISTRY B, 2006, 110 (02) :831-836

[4] Blue Photoluminescence from Chemically Derived Graphene Oxide [J].

Eda, Goki ;

Lin, Yun-Yue ;

Mattevi, Cecilia ;

Yamaguchi, Hisato ;

Chen, Hsin-An ;

Chen, I-Sheng ;

Chen, Chun-Wei ;

Chhowalla, Manish .

ADVANCED MATERIALS, 2010, 22 (04) :505-+

[5] Poly(ethylenimine) and its role in gene delivery [J].

Godbey, WT ;

Wu, KK ;

Mikos, AG .

JOURNAL OF CONTROLLED RELEASE, 1999, 60 (2-3) :149-160

[6] Facile synthesis of highly emissive carbon dots from pyrolysis of glycerol; gram scale production of carbon dots/mSiO2 for cell imaging and drug release [J].

Lai, Chih-Wei ;

Hsiao, Yi-Hsuan ;

Peng, Yung-Kang ;

Chou, Pi-Tai .

JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (29) :14403-14409

[7]

Lakowicz J.R., 2006, Principles of Fluorescence Spectroscopy, V3rd, DOI DOI 10.1007/978-0-387-46312-4

[8] Carbon nanodots: synthesis, properties and applications [J].

Li, Haitao ;

Kang, Zhenhui ;

Liu, Yang ;

Lee, Shuit-Tong .

JOURNAL OF MATERIALS CHEMISTRY, 2012, 22 (46) :24230-24253

[9] Nano-carrier for gene delivery and bioimaging based on carbon dots with PEI-passivation enhanced fluorescence [J].

Liu, Changjun ;

Zhang, Peng ;

Zhai, Xinyun ;

Tian, Feng ;

Li, Wenchen ;

Yang, Jianhai ;

Liu, Yuan ;

Wang, Hongbo ;

Wang, Wei ;

Liu, Wenguang .

BIOMATERIALS, 2012, 33 (13) :3604-3613

[10] Fluorescent carbon nanoparticles derived from candle soot [J].

Liu, Haipeng ;

Ye, Tao ;

Mao, Chengde .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (34) :6473-6475

← 1 2 3 →