Dopamine regulation of social choice in a monogamous rodent species

被引:82
作者
Aragona, Brandon J. [1 ,2 ]
Wang, Zuoxin [3 ,4 ]
机构
[1] Univ Michigan, Dept Psychol, Ann Arbor, MI 48109 USA
[2] Univ Michigan, Program Neurosci, Ann Arbor, MI 48109 USA
[3] Florida State Univ, Dept Psychol, Tallahassee, FL 32306 USA
[4] Florida State Univ, Program Neurosci, Tallahassee, FL 32306 USA
基金
美国国家卫生研究院;
关键词
nucleus accumbens; prairie vole; monogamy; social attachment; pair bond; social decision making; social neuroeconomics; VOLES MICROTUS-OCHROGASTER; FEMALE PRAIRIE VOLES; NUCLEUS-ACCUMBENS DOPAMINE; PAIR BOND FORMATION; PARTNER-PREFERENCE FORMATION; DEPENDENT PROTEIN-KINASE; MATERNAL-BEHAVIOR; DECISION-MAKING; MEADOW VOLES; NEURAL BASIS;
D O I
10.3389/neuro.08.015.2009
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
There is growing appreciation that social decision making in humans is strongly influenced by hedonic and emotional processing. The field of social neuroeconomics has shown that neural systems important for reward are associated with social choice and social preferences in humans. Here, we show that the neurobiology of social preferences in a monogamous rodent species, the prairie vole, is also regulated by neural systems involved in reward and emotional processing. Specifically, we describe how mesolimbic dopamine transmission differentially mediates the formation and maintenance of monogamous pair bonds in this species. Thus, reward processing exerts tremendous regulation over social choice behaviors that serve as the foundation of a rather complex social organization. We conclude that prairie voles are an excellent model system for the neuroscience of social choice and that complex social decision-making can be robustly explained by reward and hedonic processing.
引用
收藏
页数:11
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