The Magnitude of mTORC1 Signalling May Predict the Response to Isotretinoin Treatment in Patients with Hidradenitis Suppurativa

被引：10
作者：
De Vita, Valerio [1 ]
Melnik, Bodo C. [2 ]
机构：
[1] Univ Naples Federico II, Dermatol Unit, Naples, Italy
[2] Univ Osnabruck, Dept Dermatol Environm Med & Hlth Theory, Osnabruck, Germany
来源：
DERMATOLOGY | 2017年 / 233卷 / 05期
关键词：
Hidradenitis suppurativa; Isotretinoin; mTOR signalling; FoxO1; ACNE-VULGARIS; GROWTH; FOXO1; METABOLISM; EXPRESSION; APOPTOSIS; METFORMIN; RAPAMYCIN; TARGET; MODE;
D O I：
10.1159/000484408
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
引用
收藏
页码：399 / 400
页数：2
相关论文
共 28 条
[1]  
[Anonymous], 2014, Journal of Endocrinology, Diabetes and Obesity
[2]   MAMMALIAN TARGET OF RAPAMYCIN IN INFLAMMATORY SKIN CONDITIONS [J].
Balato, A. ;
Di Caprio, R. ;
Lembo, S. ;
Mattii, M. ;
Megna, M. ;
Schiattarella, M. ;
Tarantino, G. ;
Balato, N. ;
Ayala, F. ;
Monfrecola, G. .
EUROPEAN JOURNAL OF INFLAMMATION, 2014, 12 (02) :341-350
[3]   Are There Indications for Isotretinoin Treatment of Hidradenitis Suppurativa? [J].
Boer, Jurr .
DERMATOLOGY, 2017, 233 (2-3) :111-112
[4]   Apoptosis in the hair follicle [J].
Botchkareva, Natalia V. ;
Ahluwalia, Gurpreet ;
Shander, Douglas .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2006, 126 (02) :258-264
[5]   Should hidradenitis suppurativa/acne inversa best be renamed as "dissecting terminal hair folliculitis"? [J].
Chen, WenChieh ;
Plewig, Gerd .
EXPERIMENTAL DERMATOLOGY, 2017, 26 (06) :544-547
[6]   mTOR signaling in disease [J].
Dazert, Eva ;
Hall, Michael N. .
CURRENT OPINION IN CELL BIOLOGY, 2011, 23 (06) :744-755
[7]   Low glycaemic diet and metformin therapy: a new approach in male subjects with acne resistant to common treatments [J].
Fabbrocini, G. ;
Izzo, R. ;
Faggiano, A. ;
Del Prete, M. ;
Donnarumma, M. ;
Marasca, C. ;
Marciello, F. ;
Savastano, R. ;
Monfrecola, G. ;
Colao, A. .
CLINICAL AND EXPERIMENTAL DERMATOLOGY, 2016, 41 (01) :38-42
[8]   Interplay between FOXO, TOR, and Akt [J].
Hay, Nissim .
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2011, 1813 (11) :1965-1970
[9]   A New Perspective on Isotretinoin Treatment of Hidradenitis Suppurativa: A Retrospective Chart Review of Patient Outcomes [J].
Huang, Christina M. ;
Kirchhof, Mark G. .
DERMATOLOGY, 2017, 233 (2-3) :120-125
[10]   Evaluation of biophysical skin parameters and assessment of hair growth in patients with acne treated with isotretinoin [J].
Kmiec, Malgorzata L. ;
Pajor, Anna ;
Broniarczyk-Dyla, Grazyna .
POSTEPY DERMATOLOGII I ALERGOLOGII, 2013, 30 (06) :343-349
123