Finegoldia magna, an early post-operative cause of infectious endocarditis: Report of two cases and review of the literature

被引:19
作者
Fournier, Pierre-Edouard [1 ]
Van La, My [1 ]
Casalta, Jean-Paul [1 ]
Richet, Herve [1 ]
Collart, Frederic [2 ]
Raoult, Didier [1 ]
机构
[1] Marseille Hop La Timone, Hop La Timone, F-13385 Marseille 5, France
[2] Hop Enfants La Timone, Serv Cardiol & Chirurg Thorac, Marseille, France
关键词
Blood-culture-negative endocarditis; Finegoldia magna; PCR;
D O I
10.1016/j.anaerobe.2008.11.001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We report two cases of infectious endocarditis (IE) on prosthetic valves caused by Finegoldia magna. The diagnosis was obtained by detection of the bacterium in valvular biopsies using 165 rRNA PCR amplication and sequencing, and prolonged culture. Five other cases were previously published in the literature. Following analysis of these seven cases, F. magna endocarditis presented as a subacute endocarditis, developing early (60 days) following valvular replacement (85%), with an elevated mortality (28%). Our report highlights the potential role of F. magna in early post-surgical endocarditis on prosthetic valves. (C) 2008 Elsevier Ltd. All rights reserved.
引用
收藏
页码:310 / 312
页数:3
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