Facile lipase catalysed syntheses of (S)-(+)-4-hydroxy-β-ionone and (S)-(+)-4-hydroxy-β-damascone: chiral flavorants and synthons

被引：12

作者：

More, Gauri P. ^{[1
]}

Bhat, Sujata V. ^{[1
]}

机构：

[1] Mumbai Univ, Lab Adv Res Nat & Synthet Chem, VG Vaze Coll, Bombay 400081, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 32期

关键词：

Transesterification; Pig pancreatic lipase; (S)-(+)-4-Hydroxy-beta-damascone; (S)-(+)-4-Hydroxy-beta-ionone; Flavorants; ABSOLUTE-CONFIGURATION; FORSKOLIN; ALPHA;

D O I：

10.1016/j.tetlet.2013.05.089

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioselective syntheses of (S)-(+)-4-hydroxy-beta-ionone and (S)-(+)-4-hydroxy-beta-damascone have been achieved through pig pancreatic lipase catalysed trans-esterification. These molecules find utility as constituent in fruit-type fragrance and flavor formulations and as chiral synthons in asymmetric synthesis of bioactive terpenoids. (C) 2013 Elsevier Ltd. All rights reserved.

引用

页码：4148 / 4149

页数：2