Carbon Nano-Onions as Nontoxic and High-Fluorescence Bioimaging Agent in Food Chain-An In Vivo Study from Unicellular E. coli to Multicellular C-elegans

被引：73

作者：

Sonkar, Sumit Kumar ^{[1
]}

Ghosh, Mitrajit ^{[1
]}

Roy, Manas ^{[1
]}

Begum, Ameerunisha ^{[1
]}

Sarkar, Sabyasachi ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kanpur 208016, Uttar Pradesh, India

来源：

MATERIALS EXPRESS | 2012年 / 2卷 / 02期

关键词：

Water Soluble; Carbon Nano-Onions; Escherichia coli; Caenorhabditis elegans; Non-Toxic; Fluorescence; Bioimaging; NEMATODE CAENORHABDITIS-ELEGANS; COVALENT FUNCTIONALIZATION; GENE-EXPRESSION; NANOTUBES; TOXICITY; NANODIAMONDS; GROWTH; HYDROXYAPATITE; NANOPARTICLES; SOIL;

D O I：

10.1166/mex.2012.1064

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Carbon nano-onions, as a newly-emergent member of the carbon family, have attracted attention in its both dry and wet applications. Here we report in vivo effects of water-soluble carbon nano-onions (wsCNOs) introduced in common food web of two model organisms: unicellular Escherichia coli (E. coli) and multicellular Caenorhabditis elegans (C. elegans). At first, CNOs are fed to E. coli and, subsequently, the E. coli are fed to C. elegans. It is found that wsCNOs serve as highly-fluorescent bioimaging agent. The results do not reflect any toxic effect of wsCNOs on the growth of these organisms suggesting new avenues in nanotoxicology research and biomedical application including drug delivery.

引用

页码：105 / 114

页数：10

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