One Pot Regioselective Synthesis of a Small Library of Dibenzo[b,f][1,4]thiazepin-11(10H)-ones via Smiles Rearrangement

被引：14

作者：

Zhao, Yongmei ^{[1
]}

Dai, Qiaoling ^{[1
]}

Chen, Zhi ^{[1
]}

Zhang, Qihui ^{[1
]}

Bai, Yongcheng ^{[1
]}

Ma, Chen ^{[1
]}

机构：

[1] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China

来源：

ACS COMBINATORIAL SCIENCE | 2013年 / 15卷 / 02期

基金：

中国国家自然科学基金;

关键词：

metal-free process; benzoic-fused seven-membered lactams; Smiles rearrangement; DERIVATIVES; INHIBITORS; SERIES; AGENTS;

D O I：

10.1021/co300139s

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A facile and efficient method has been developed for the synthesis of a small library of dibenzo[b,f][1,4]thiazepin-11(10H)-ones via Smiles rearrangement. Compounds were obtained in excellent isolated yields (70%-92%) under metal-free conditions. More specifically, this transition metal-free process relates to an environmentally friendly, economical, and efficient method for preparing benzoic-fused seven-membered lactams.

引用

页码：130 / 134

页数：5

共 35 条

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