Tumor-cell targeting polydiacetylene micelles encapsulated with an antitumor drug for the treatment of ovarian cancer

被引：29
|
作者：
Yao, Defan
Li, Shang
Zhu, Xiaomin
Wu, Junchen [1 ]
Tian, He
机构：
[1] East China Univ Sci & Technol, Key Labs Adv Mat, Shanghai 200237, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 07期
关键词：
DELIVERY; THERAPY; CHEMOTHERAPY; CISPLATIN; SENSOR;
D O I：
10.1039/c6cc08581d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Peptide functionalized polydiacetylene (PDA) micelles encapsulated with camptothecin (CPT) kill ovarian cancer cells by the lysosome release of anticancer drug CPT. Moreover, the sub-30 nm PDA micelles penetrate efficiently into a tumor for enhanced therapeutic efficacy.
引用
收藏
页码：1233 / 1236
页数：4
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