Serendipitous Recanalization of Basilar Artery Occlusion

被引：1
作者：
Switzer, Jeffrey A. [1 ]
Forseen, Scott E. [2 ]
Bruno, Askiel [1 ]
Hess, David C. [1 ]
机构：
[1] Georgia Regents Univ, Dept Neurol, Augusta, GA USA
[2] Georgia Regents Univ, Dept Radiol, Augusta, GA USA
来源：
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES | 2013年 / 22卷 / 08期
关键词：
Basilar artery occlusion; thrombolytic therapy; acute stroke; tenecteplase; ACUTE ISCHEMIC-STROKE; INTRAVENOUS THROMBOLYSIS; TENECTEPLASE; THERAPY; POSTERIOR; OUTCOMES; TRIAL;
D O I：
10.1016/j.jstrokecerebrovasdis.2013.06.019
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Objective: To describe a case of recanalization of a basilar artery occlusion with intravenous (IV) tenecteplase. Case: A 74-year-old man with a history of cardiomyopathy presented to an outside hospital with acute vertigo, dysarthria, gaze deviation, and ataxia. Computerized tomography arteriography demonstrated occlusion of the proximal basilar artery. IV tissue plasminogen activator was ordered; however, the patient received a cardiac dose of IV tenecteplase. The patient was transferred to our facility, whereby symptoms resolved, and repeat computerized tomography arteriography displayed recanalization of the basilar artery. Conclusions: Tenecteplase has enhanced biochemical and pharmacokinetic properties that may be ideal for treatment of basilar artery occlusion and should be further investigated in a randomized clinical trial.
引用
收藏
页码：E671 / E673
页数：3
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