Vitamin B deficiency causes neural cell loss and cognitive impairment in the developing rat

被引:30
作者
Daval, Jean-Luc [1 ,2 ]
Blaise, Sebastien [1 ,2 ]
Gueant, Jean-Louis [1 ,2 ,3 ]
机构
[1] Nancy Univ, Inst Natl Sante & Rech Med, U724, Fac Med, F-54500 Vandoeuvre Les Nancy, France
[2] Nancy Univ, Ctr Hosp Univ Nancy, F-54500 Vandoeuvre Les Nancy, France
[3] Inst Res Mental Retardat & Brain Aging, Oasi Maria SS, Ist Ricovero & Cura Carattere Sci, I-94018 Troina, Italy
关键词
INHIBITS PROLIFERATION; BRAIN; MICE;
D O I
10.1073/pnas.0809217106
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
引用
收藏
页码:E1 / E1
页数:1
相关论文
共 5 条
[1]   Gestational vitamin B deficiency leads to homocysteine-associated brain apoptosis and alters neurobehavioral development in rats [J].
Blaise, Sbastien A. ;
Nedelec, Emmanuelle ;
Schroeder, Henri ;
Alberto, Jean-Marc ;
Bossenmeyer-Pourie, Carine ;
Gueant, Jean-Louis ;
Daval, Jean-Luc .
AMERICAN JOURNAL OF PATHOLOGY, 2007, 170 (02) :667-679
[2]   Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase [J].
Kronenberg, Golo ;
Harms, Christoph ;
Sobol, Robert W. ;
Cardozo-Pelaez, Fernando ;
Linhart, Heinz ;
Winter, Benjamin ;
Balkaya, Mustafa ;
Gertz, Karen ;
Gay, Shanna B. ;
Cox, David ;
Eckart, Sarah ;
Ahmadi, Michael ;
Juckel, Georg ;
Kempermann, Gerd ;
Hellweg, Rainer ;
Sohr, Reinhard ;
Hoertnagl, Heide ;
Wilson, Samuel H. ;
Jaenisch, Rudolf ;
Endres, Matthias .
JOURNAL OF NEUROSCIENCE, 2008, 28 (28) :7219-7230
[3]   Folate deficiency inhibits proliferation of adult hippocampal progenitors [J].
Kruman, II ;
Mouton, PR ;
Emokpae, R ;
Cutler, RG ;
Mattson, MP .
NEUROREPORT, 2005, 16 (10) :1055-1059
[4]   Homocysteine inhibits proliferation of neuronal precursors in the mouse adult brain by impairing the basic fibroblast growth factor signaling cascade and reducing extracellular regulated kinase 1/2-dependent cyclin E expression [J].
Rabaneda, Luis G. ;
Carrasco, Manuel ;
Lopez-Toledano, Miguel A. ;
Murillo-Carretero, Maribel ;
Ruiz, Felix A. ;
Estrada, Carmen ;
Castro, Carmen .
FASEB JOURNAL, 2008, 22 (11) :3823-3835
[5]   B-vitamin deficiency causes hyperhomocysteinemia and vascular cognitive impairment in mice [J].
Troen, Aron M. ;
Shea-Budgell, Melissa ;
Shukitt-Hale, Barbara ;
Smith, Donald E. ;
Selhub, Jacob ;
Rosenberg, Irwin H. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (34) :12474-12479