Growth hormone and its receptors in the central nervous system - Location and functional significance

被引：105

作者：

Nyberg, F ^{[1
]}

Burman, P ^{[1
]}

机构：

[1] UNIV UPPSALA HOSP, DEPT INTERNAL MED, UPPSALA, SWEDEN

来源：

HORMONE RESEARCH | 1996年 / 45卷 / 1-2期

关键词：

brain; CNS effects; cerebrospinal fluid; receptors; deficiency; therapy; beta-endorphin; opioid peptides; homovanillic acid;

D O I：

10.1159/000184753

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

During the past few years, there has been increasing interest in functions that growth hormone (GH) may play in the central nervous system, Accumulating evidence that the hormone may pass the blood-brain barrier and the psychological improvements seen in adults following GH therapy have received particular attention. This paper will review our recent studies on GH receptors in the human and rat brain. A recent study on the effects of GH treatment in adult growth hormone-deficient patients on quality of life and cerebrospinal fluid levels of various hormones and neurotransmitters is also included.

引用

页码：18 / 22

页数：5

共 28 条

[1] RAT GROWTH-HORMONE AND HYPOTHALAMIC CATECHOLAMINE NERVE-TERMINAL SYSTEMS - EVIDENCE FOR RAPID AND DISCRETE REDUCTIONS IN DOPAMINE AND NORADRENALINE LEVELS AND TURNOVER IN THE MEDIAN-EMINENCE OF THE HYPOPHYSECTOMIZED MALE-RAT [J].