Arthrogryposis multiplex congenita in Aberdeen Angus cattle in Uruguay

被引:0
作者
Romero, Agustin [1 ]
Briano, Carolina [1 ]
Quintela, Fernando Dutra [1 ]
机构
[1] Div Labs Vet DILAVE Miguel C Rubino, Lab Reg Este, Avelino Miranda 2045, Treinta Y Tres 33000, Uruguay
来源
PESQUISA VETERINARIA BRASILEIRA | 2020年 / 40卷 / 06期
关键词
Arthrogryposis multiplex congenita; bovine; Aberdeen Angus; cattle; Uruguay; hereditary diseases; INTRAUTERINE INFECTION; NEUROLOGICAL DISEASES; RUMINANT LIVESTOCK; ETIOLOGY; MUTATION; VIRUS; AGRIN;
D O I
10.1590/1678-5150-PVB-6636
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Arthrogryposis multiplex congenita is reported for the first time in the Aberdeen Angus (AA) breed in Uruguay. In a commercial herd of 30 purebred Aberdeen Angus cows, two calves with severe musculoskeletal malformations died at birth. The cows had been inseminated using semen imported from Argentina from one elite AA sire only. At necropsy, one calf showed severe muscular atrophy, arthrogryposis affecting all four limbs and the spine, kyphoscoliosis and torticollis. Histopathology showed muscular atrophy with marked fiber size variation and abundant fibroadipose fibers. The central nervous system only showed congestion and edema due to dystocia, whereas the peripheral nerves and the number of motor neurons in the spinal appeared normal. DNA analysis confirmed arthrogryposis multiplex congenita. It is concluded that disease in Aberdeen Angus cattle is due to failure in the neuromuscular junction.
引用
收藏
页码:426 / 429
页数:4
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