APPLICATION OF EVOLUTIONARY GAMES TO MODELING CARCINOGENESIS

被引:15
作者
Swierniak, Andrzej [1 ]
Krzeslak, Michal [1 ]
机构
[1] Silesian Tech Univ, Dept Automat Control, PL-44101 Gliwice, Poland
关键词
Evolutionary games; biomathematical modeling; cellular automata; tumorigenesis; polymorphism; BIOLOGY; TUMORS;
D O I
10.3934/mbe.2013.10.873
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We review a quite large volume of literature concerning mathematical modelling of processes related to carcinogenesis and the growth of cancer cell populations based on the theory of evolutionary games. This review, although partly idiosyncratic, covers such major areas of cancer-related phenomena as production of cytotoxins, avoidance of apoptosis, production of growth factors, motility and invasion, and intra- and extracellular signaling. We discuss the results of other authors and append to them some additional results of our own simulations dealing with the possible dynamics and/or spatial distribution of the processes discussed.
引用
收藏
页码:873 / 911
页数:39
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