Pre-eclampsia is a common condition, unique to pregnancy, and almost unique among medical conditions in that we have, at best, only a patchy knowledge of the underlying aetiology and pathophysiology. In this chapter, established and new hypotheses will be discussed and the recent supporting evidence for each will be reviewed. The principal systems affected by pre-eclampsia, namely the cardiovascular, coagulation, liver and renal systems, together with cerebral manifestations of this disease will be discussed in turn.
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Univ Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, JapanUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan
Nakashima, Akitoshi
Aoki, Aiko
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Univ Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, JapanUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan
Aoki, Aiko
Kusabiraki, Tae
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Univ Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, JapanUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan
Kusabiraki, Tae
Shima, Tomoko
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Univ Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, JapanUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan
Shima, Tomoko
Yoshino, Osamu
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Univ Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, JapanUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan
Yoshino, Osamu
Cheng, Shi-Bin
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Brown Univ, Women & Infants Hosp, Dept Pediat, Providence, RI 02908 USAUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan
Cheng, Shi-Bin
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Sharma, Surendra
Saito, Shigeru
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Univ Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, JapanUniv Toyama, Dept Obstet & Gynecol, Fac Med, 2630 Sugitani, Toyama 9300194, Japan