Task-induced deactivation and the "resting" state

被引:66
作者
Binder, Jeffrey R. [1 ]
机构
[1] Med Coll Wisconsin, Dept Neurol, 9200 W Wisconsin Ave, Milwaukee, WI 53226 USA
关键词
Functional MRI; Resting state; Mind-wandering; Semantics; Memory; STREAM-OF-CONSCIOUSNESS; HUMAN BRAIN; DEFAULT NETWORK; EPISODIC MEMORY; FRONTAL-CORTEX; LANGUAGE; ORGANIZATION; ACTIVATION; ANATOMY; COMPREHENSION;
D O I
10.1016/j.neuroimage.2011.09.026
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Task-induced decreases in blood flow and the widespread use of "resting" baselines produced unexpected and discrepant results in early cognitive imaging studies, especially in language comprehension experiments. Here I describe from a personal perspective some of the events and thought processes leading to the first hypothesis-driven fMRI study of the "resting" state. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:1086 / 1091
页数:6
相关论文
共 60 条
[1]   DISTRIBUTED ANATOMY OF TRANSCORTICAL SENSORY APHASIA [J].
ALEXANDER, MP ;
HILTBRUNNER, B ;
FISCHER, RS .
ARCHIVES OF NEUROLOGY, 1989, 46 (08) :885-892
[2]  
ANDREASEN NC, 1995, AM J PSYCHIAT, V152, P1576
[3]   The Brain's Default Network and Its Adaptive Role in Internal Mentation [J].
Andrews-Hanna, Jessica R. .
NEUROSCIENTIST, 2012, 18 (03) :251-270
[4]  
[Anonymous], 1992, ADAPTED MIND
[5]   INFORMATION THEORY AND STIMULUS-INDEPENDENT THOUGHT [J].
ANTROBUS, JS .
BRITISH JOURNAL OF PSYCHOLOGY, 1968, 59 :423-&
[6]   STUDIES IN STREAM OF CONSCIOUSNESS - EXPERIMENTAL ENHANCEMENT AND SUPPRESSION OF SPONTANEOUS COGNITIVE PROCESSES [J].
ANTROBUS, JS ;
SINGER, JL ;
GREENBER.S .
PERCEPTUAL AND MOTOR SKILLS, 1966, 23 (02) :399-&
[7]  
Binder J. R., 1996, Neurology, V46, pA423
[8]   Where Is the Semantic System? A Critical Review and Meta-Analysis of 120 Functional Neuroimaging Studies [J].
Binder, Jeffrey R. ;
Desai, Rutvik H. ;
Graves, William W. ;
Conant, Lisa L. .
CEREBRAL CORTEX, 2009, 19 (12) :2767-2796
[9]   Conceptual processing during the conscious resting state: A functional MRI study [J].
Binder, JR ;
Frost, JA ;
Hammeke, TA ;
Bellgowan, PSF ;
Rao, SM ;
Cox, RW .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1999, 11 (01) :80-93
[10]   LATERALIZED HUMAN BRAIN LANGUAGE SYSTEMS DEMONSTRATED BY TASK SUBTRACTION FUNCTIONAL MAGNETIC-RESONANCE-IMAGING [J].
BINDER, JR ;
RAO, SM ;
HAMMEKE, TA ;
FROST, JA ;
BANDETTINI, PA ;
JESMANOWICZ, A ;
HYDE, JS .
ARCHIVES OF NEUROLOGY, 1995, 52 (06) :593-601